Not an attempt to tell you what to do, but I would never even have tried the CLR. I don't know how toxic that would be to the frog but I wouldn't take the chance just for the tank's esthetic's sake. Seems to me that even if you think you've wiped it well, there will always be some small residue left on the glass and leopard frogs are pretty much "one with the water". Meaning whatever is in your water is in them too. I keep leopard frogs and green frogs too.
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