I might be a newb to the Viv world, but I know alot of people have used fiberglass resins in reef tanks to build rock walls. These guys wouldn't risk thousands of dollars worth of fish if it wasn't safe. So it is safe to use after some curing..
The thing is there are 2 types of resin available. PolyUrethane and Epoxy. You want to make sure you have epoxy resin, not the cheap stuff for cars...
This brings up another point though, fish don't have claws and aren't likely to disturb the surface where a lizard might be...
Not sure if I helped or made it worse....
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